About Us

Our Publications

Pre-2000

  • Shapiro, C.M., Moore, A.T., Mitchell, D. and Yodaiken, M.L. How well does man thermoregulate during sleep? Experientia, 3O:1279-128l, 1974
  • Shapiro, C.M. And Rosendorff, C.Local hypothalamic blood flow during sleep. Electroenceph. Clinical Neurophysiology, 39:365-369, 1975
  • Shapiro, C.M. And Hepburn, H.R. Sleep in a Schooling Fish, Tilapia Mossambica. Physiology and Behaviour, 16:613-615, 1976
  • Shapiro, C. And Girdwood, P. Protein synthesis in rat brain during sleep. Neuropharmacology, 20:457-460, 1981
  • Shapiro, C.M., Bortz, R., Mitchell, D., Bartel, P. And Jooste, P. Slow-wave sleep: a recovery process after exercise. Science, 214:1253-1254, 1981
  • Shapiro, C.M., Goll, C.C., Cohen, G. And Oswald, I. Heat production during sleep.Journal of Applied Physiology, 56:671-677, 1984
  • Shapiro, C.M., Catterall, J.R., Montgomery, I., Raab, G. And Douglas, N.J. Do asthmatics suffer bronchoconstriction during rapid eye movement sleep? British Medical Journal, 292:ll6l-ll65, 1986
  • Shapiro, C.M., Blake, F., Fossey, E. and Adams, B. Daylight saving time in psychiatric illness. Journal of Affective Disorders, 19:177-181, 1990
  • Shapiro, C.M. And Dement, W.C. Impact and epidemiology of sleep disorders. British Medical Journal, 306:1604-1607, 1993
  • Chapman J and O’Reilly JF The Role of oximetry and the Epworth sleepiness scale in screening for Sleep Apnoea / Hypopnoea syndrome.. Abstract at British Sleep Society meeting, Oxford 1999.
  • Chapman M and O’Reilly JF The effects of nasal continuous positive pressure (nCPAP) on the overnight pulse rate, as measured by pulse oximetry in patients with obstructive sleep apnoea.. Abstract at British Sleep Society Meeting, Oxford in September 1999.

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2000 – 2009

  • Ebrahim IO, The three faces of Memory Disorder; Health and Aging, 2000, 14:24 -27;
  • Murphy R, Mackway-Jones K, Sammy I, Driscoll P, Gray A, O’Driscoll R, O’Reilly J, Niven R, Bentley A, Brear G, Kishen R.Emergency oxygen therapy for the breathless patient. Guidelines prepared by North West Oxygen Group. Emerg Med J. 2001 Nov; 18(6): 421-3.
  • Ebrahim IO, Howard R S, Kopelman M D, Sharief M K, and Williams A J. The hypocretin/orexin system. J R Soc Med 2002 95: 227-230;
  • Ebrahim IO, de Lacy S, Semra Y K, Howard R S, Sharief M K, and Williams AJ.CSF Hypocretin levels in Neurologic and Psychiatric conditions, SLEEP 2002;
  • Ebrahim IO, de Lacy S, Semra Y K, Howard R S, Sharief M K, and Williams A J.Narcolepsy with cataplexy, Monosymptomatic Narcolepsy and Primary Hypersomnia: A prospective study in 24 patients including CSF hypocretin levels, SLEEP 2002; 25:
  • Ebrahim IO, Memory Disorders in Psychiatric Practice, BJPsych 2002; 181: 177-178;
  • Ebrahim IO, Sharief MK, de Lacy S, Semra YK, Howard RS, Kopelman MD, Williams AJ. Hypocretin (Orexin) Deficiency in Narcolepsy and Primary Hypersomnia. JNNP 2003; 74(1): 127-130.
  • Shapiro, C.M., Trajanovic, N.N. And Fedoroff, J.P. Sexsomnia: A New Parasomnia. Canadian Journal of Psychiatry 48;5:311-317, 2003
  • Ebrahim IO, Williams AJ, et al. CSF Hypocretin (Orexin) in Neurological and Psychiatric disorders. JSR 2003; 12(1).
  • Ebrahim IO, Fisher JP, de Lacy S, Williams AJ. A prospective, randomized, trial comparing the effectiveness of Cognitive Behaviour Therapy, Pharmacologic Treatment and Combination therapy in patients with Primary Insomnia. SLEEP (2003)
  • Williams AJ, Oka Y, Howard RS, Soliman MGG, de Lacy S, Ebrahim IO. REM Sleep Behaviour Disorder – Characteristics of a series of consecutive referrals to a Specialist Sleep disorders Centre in the UK, SLEEP (2003)
  • Ebrahim IO, de Lacy S, Howard RS, Sharief MK, Williams AJ. CSF Hypocretin (Orexin) in Disorders of Excessive Daytime Sleepiness. SLEEP (2003).
  • Nightingale S, Orgill JC, Ebrahim IO, Williams AJ. The Association between Narcolepsy and REM Sleep Behaviour Disorder (RBD). SLEEP (2004)
  • Stradling J, Schneerson J, O’Reilly J. Eds. Sleep Medicine Study Programme. Part 3: Obstructive Sleep Apnoea. Interactive CD-ROM. Taylor Patten Communications 2004
  • Thannickal TC, Mayhew J Blouin A, Nienhuis R, Williams AJ, Ebrahim IO, Siegel JM. Distribution of Hypocretin (Orexin) Immunoreactivity In The Hypothalamus Of Normal And Narcoleptic Horse. SLEEP (2004)
  • Orgill JC, Bath J, Ebrahim IO, de Lacy SF, Williams AJ. The role of Actigraphy in the study of Sleep and Circadian Rhythms. SLEEP (2004).
  • Ebrahim IO. The Management of Excessive Daytime Sleepiness. Drugs & Therapeutics Bulletin. 2004 June;
  • Nightingale S, Williams AJ, Orgill JC, Ebrahim IO, de Lacy S. The association between narcolepsy and REM behaviour disorder (RBD) Sleep Medicine (2005)
  • Ebrahim IO, Peacock KW. REM Sleep Behavior Disorder – Psychiatric Presentations: A Case Series from the United Kingdom Journal of Clinical Sleep Medicine, Vol. 1, No. 1, 2005
  • Ebrahim IO, Peacock KW, Williams AJ. Post-traumatic Narcolepsy: 2 case reports and a mini-review. Journal of Clinical Sleep Medicine, Vol. 1, No. 2, 2005
  • Ebrahim IO, Williams AJ, Peacock KW, Maldonado CC. Driver Sleepiness in South African Commercial Drivers: A two stage screening study. SLEEP 28: 165 (2005)
  • Ebrahim IO, de Lacy S, et al. CSF Hypocretin (Orexin) in disorders of excessive daytime sleepiness. SLEEP 28: 216 (2005)
  • Wilson W, Ebrahim IO, Fenwick P, Marks RL. Violence, Sleepwalking and the Criminal Law. Criminal Law Review (August 2005)
  • Ebrahim IO, Wilson W, Fenwick PB, Peacock KW, Marks RL. Sleep related violence, Alcohol, Automatism and the Law. Criminal Law Review (2005)
  • Ebrahim IO. Somnambulistic Sexual Behaviour (Sexsomnia). Journal of Clinical Forensic Medicine 13 (2006) 219–224
  • Hajak G, Ebrahim IO, Vincent S & Hibberd M. Ramelteon, unlike Zopiclone, has no Effect on Body Sway at Peak Plasma Levels in Insomnia Patients. SLEEP (2007)
  • Engleman, H.M., Hill, E.A., Ebrahim, I.O., Idzikowski, C. Improvement in polysomnographic sleep quality with a mattress cooling device. Journal of Sleep Research 2008; 17 (suppl.1): 235.
  • Engleman, H.M., Rosman, K., Bruning, A., Ameen, O., Chakkal, P., Williams, A.J., Hill, E.A., Ebrahim, I.O. Patient audit of the Sigma sleep centres, South Africa; sleep apnoea/hypopnoea syndrome (SAHS) and relationships with subjective symptom ratings. Journal of Sleep Research 2008; 17 (suppl.1): 161.
  • Ganjavi H., Shapiro CM.Hypocretin/Orexin: A molecular link between sleep, energy regulation, and pleasure. Journal Neuropsychiatry Clinical Neurosci, 19:413-419, 2007
  • J.Wilding, JF O’Reilly.Sleep Apnoea, Obesity, Diabetes and Metabolic Syndrome. European Endocrine Disease 2007; ii: 72-75.
  • Chung, F., Yegneswaran, B., Liao, P., Chung, Sa., Vairavanathan, S.,  Islam, S., Khajehdehi, A., Shapiro, CM. STOP questionnaire: a tool to screen patients for obstructive sleep apnea. Anesthesilogy,108(5):812-821, 2008
  • Ebrahim IO & Fenwick PB. Sleep-related automatism and the law. MedSciLaw 2008; 48(2):124-36.
  • Ebrahim IO. Ramelteon: A novel treatment for Insomnia. Future Neurology (January 2008)
  • Bonakis A, Howard RS, Ebrahim IO, Merritt S, Williams AJ. REM sleep behaviour disorder (RBD) and its associations in young patients. Sleep Medicine, Volume 10, Issue 6, June 2009, Pages 641-645
  •   Rahman SA., Kayumov L., Tchmoutina EA., Shapiro CM.Clinical efficacy of dim light melatonin onset testing in diagnosing delayed sleep phase syndrome. Sleep Medicine, 10: 549-555, 2009
  • I Iskandar, AP Hall, J O’Reilly, A Barnett, M Allen, R Andrews, P Grunstein, K Lewis, N Goenka and JP Wilding.Obstructive sleep apnoea in patients with type 2 diabetes: aetiology and implications for clinical care. Diabetes, Obesity and Metabolism 2009; 11: 733–741.
  • John O’Reilly.Sleep apnoea and sleep breathing disorders. British Journal of Hospital Medicine 2009; Vol 70; 6: 234-40. 100.

  

2010 – Present

  • Hoeve P, Dorffner G, Ebrahim IO, Hajak G and Dingemanse J. Orexin Receptor Antagonism, a New Sleep-Enabling Paradigm: A Proof-of-Concept Clinical Trial. (2012). Clinical Pharmacology & Therapeutics. 2010
  • Yegneswaran B, Shapiro C. Which is the greater sin? Continuing to smoke or non-compliance with CPAP therapy? J Clin Sleep Med. 15;7(3):315-6, 2011
  • Wilkinson K., Shapiro C. Nonrestorative sleep: symptom or unique diagnostic entity?Sleep Med. 13(6): 561-569, 2012
  • Ebrahim IO & Fenwick PB Letter to the Editor. Sleep Related Violence, Alcohol and Sleepwalking. Brain (2012)
  • Drakatos P, Suri A, Higgins SE, Ebrahim IO, Muza RT, Kosky CA, Williams AJ, Leschziner GD. Research Paper: Sleep stage sequence analysis of sleep onset REM periods in the hypersomnias. J Neurol Neurosurg Psychiatry 2012;0:1–5. doi:10.1136/jnnp-2012-303578
  • Ebrahim IO, Shapiro CM, Williams AJ, Fenwick PB. Review: Alcohol and Sleep I: Effects on Normal Sleep, Alcohol Clin Exp Res, Vol 37, No 4, 2013: pp 539–549
  • Ebrahim IO. REVIEW: NREM Parasomnias Recent Advances and Forensic Aspects.Forensic. Curr Opinion in Pulmonary Medicine, 2013, 19:609–615. DOI:10.1097/MCP.0b013e3283659e5f
  • Lowe A, Rajaratnam S, Ebrahim IO, Hoy K, Taffe K, Fitzgerald P (2013) Can sleep disturbance in depression predict repetitive transcranial magnetic stimulation (rTMS) treatment response? Psychiatry Research 210(1):121-6
  • Kadmon G., Chung Sa., Shapiro Cm.I’M SLEEPY: A short pediatric sleep apnea questionnaire. International Journal of Pediatric Otorhinolaryngology, 78(12): 2116-2120, December 2014
  • Lowe ASW, Ebrahim IO and Williams AJ.  The Effect of Lifestyle Interventions on Obstructive Sleep Apnoea and the Metabolic Syndrome: A Systematic Review. Sleep Disorders: Treatment and Care 2014, 3:3
  • Rae D, Ebrahim I, Roden LC. Sleep: a serious contender for the prevention of obesity and non- communicable diseases. Journal of Endocrinology, Metabolism and Diabetes of South Africa.2016;. 21 (1): 1-2
  • Goril S., Zalai D., Scott L., Shapiro Cm. Sleep and melatonin secretion abnormalities in children and adolescents with fetal Alcohol spectrum disorders. Sleep Medicine, 23:59-64, July 2016
  • Chakrabarti B, Emegbo  B, Craig S, Duffy N, O’Reilly J.Pulse transit time changes in subjects exhibiting sleep disordered breathing. Respiratory Medicine 2017;122; 18-22.
  • Van Zyl LT, Chung SA, Shahid A and Shapiro CM. L-Tryptophan As Treatment for Pediatric Non-Rapid Eye Movement Parasomnia. Journal of Child and Adolescent Psychopharmacology, Vol 28(6): 395-401; 2018
  • van Wyk M, McCreesh-Toselli S, Williams S, & Ebrahim IO. The distinct roles of OSA and depression severity in day- and night-time symptomatology in OSA patients: a pilot study. Sleep Breath. DOI 10.1007/s11325-019-01924-1
  • A, Kelly JL, Turnbull CD, McMillan A, Craig SE, O’Reilly JF et al. Continuous positive airway pressure versus standard care for the treatment of people with mild obstructive sleep apnoea (MERGE): a multicentre, randomised controlled trial. Lancet Respir Med 2019 Published Online December 2, 2019 https://doi.org/10.1016/S2213-2600(19)30402-3
  • Zalai  Dn. Girand Ta., Cusimano Md., Shapiro  CM.Circadian rhythm in the assessment of post concussion insomnia: a cross-sectional Observational study. CAMJ, 10;8(1): E142-E147, March 2020

  

Books and Chapters

  • Shapiro CM. ABC of Sleep Disorders. BMJ Publishing Group, London, U.K., 1993.
  • Shapiro CM, McCall Smith, A. Forensic Aspects of Sleep. John Wiley & Sons, Chichester, England, 1997.
  • Shapiro CM Who Needs to Sleep Anyway? How Animals Sleep.Black Moss Press, Ontario, Canada, 1996.
  • Miyoshi K, Shapiro CM, Gaviria M and Morita Y (Eds.) Contemporary Neuropsychiatry. Springer Verlag, Tokyo, Japan, 2001
  • Shapiro CM, Ohayon MM, Ebrahim IO, Grunstein R.Fighting Fatigue & Sleepiness: Practical Strategies for minimising sleepiness & fatigue. Joli Joco Publications (2005)
  • Jacobson R, Ebrahim IO, Kopelman MD. Organic Psychiatric Disorders, Seminars in General Adult Psychiatry, Royal College of Psychiatrists, Gaskell (2007).
  • Stores G & Ebrahim IO. Sleep Disorders, Seminars in General adult Psychiatry, Royal College of Psychiatrists, Gaskell (2007).
  • Ebrahim IO and Fenwick PB. Forensic Issues of Sleep in Psychiatric Patients (Chapter 32) in Sleep and Mental Illness. Eds. Pandi-Perumal SR & Kramer M. (Cambridge University Press, 2010)
  • Ebrahim IO & Shapiro CM. Medico-legal consequences of Parasomnias (Chapter 10) in Parasomnias and other Movement Disorders. Eds. Thorpy M & Plazzi G. (Cambridge University Press, 2010) pp 81-98
  • Shahid A, Wilkinson K, Marcu S, and Shapiro CM. STOP, THAT and 100 other Sleep Scales. Springer, 2012
  • Ebrahim IO and Idzikowski C. Forensic Aspects of Sleep Disorders (Chapter 22) in The Encyclopedia of Sleep Science, Elservier, 2013
  • O’Reilly J. Sleep Physiology and Sleep Breathing Disorders. In: Scott-Brown’s Otorhinolarnygology and Head and Neck Surgery – Watkinson and Clarke. Tumours of the head and neck Eds. Vin Paleri and Terry Jones. (2018).
  • Ebrahim IO and Idzikowski C: Automatism (Chapter 74) in Forensic Psychiatry: Fundamentals and Clinical Practice. Eds. Puri BK and Treasaden I H. (CRC Press, 2018)
  • Idzikowski C & Ebrahim I O Sleep Science (Chapter 7) in Forensic Psychiatry: Fundamentals and Clinical Practice. Eds. Puri BK and Treasaden I H. (CRC Press, 2018)